| |
REQUIRED READING FOR LECTURES |
Imm-1 |
Parham, ch. 1, pp. 1-20; ch. 8, pp. 227-260
NEJ M articles: 1. The Immune System I 343:37-49, 2. The Immune System II 343:108-117, 3. Innate Immunity 343:338-344 |
Imm-2 |
Parham, ch. 1, pp. 20-33; ch. 8, pp. 260-277
NEJ M articles: 1. The Immune System I 343:37-49 2. The Immune System II 343:108-117 |
Imm-3 |
Parham 3rd. ed., ch. 4, pp. 95-105, 117-119. ch.5, pp. 125-127, 129-131 (sections 5-4 and 5-5) |
Imm-4 |
Parham, ch. 3, pp. 75-81. ch. 5, pp. 132-156. |
Imm-5 |
Parham, ch. 2; pp. 41-47; ch. 11, pp. 392-395 |
Meth-1 |
Small Groups: B-Groups Immunological Methods #1 (see: required group reading below and schedule for specific group assignment) |
Imm-6 |
Parham 3rd. ed., ch 3, pp. 75-81; ch. 5, pp.132-156 |
Meth-1 |
Small Groups: Immunological Methods #1 (A GROUPS) (see: required group reading below ) |
Imm-7 |
Parham 3rd. ed., ch. 1, pp. 12-23; ch. 8, pp. 210-222
NEJ M articles: T-Cell Function and Migration 343: 1020-1034
|
Meth-2 |
Small Groups: Immunological Methods #2 (B GROUPS) |
Meth-2 |
Small Groups: Immunological Methods #2 (A GROUPS) |
Imm-8 |
Parham 3rd. ed., ch. 8,
NEJ M articles: 6. T-Cell Function and Migration 343: 1020-1034;
7. Primary Immunodeficiency Diseases Due to Defects in Lymphocytes 343:1313-1324 |
Cases |
A-and B Groups (see schedule for specific group assignments; lit. list below) |
Imm-9 |
Parham 3rd. ed., ch. 2, pp. 33-42, 58-62; ch. 9, pp. 272-275
NEJ M articles: 13. Complement I 344(14): 1058-1066
14. Complement II 344(15): 1140-1144 |
Imm-10 |
Parham 3rd. ed., ch. 6 review, ch.9, ch. 11, pp. 341-346
|
Imm-11 |
Parham 3rd. ed., ch. 10, pp. 303-314; ch. 11, pp. 338-351 |
Cases |
A and B Groups (see schedule for specific group assignments; lit. list below) |
Imm-12 |
Parham 3rd. ed. ch. 11, pp. 343-376
NEJ M article: 12. Tolerance and Autoimmunity 344(9): 655-664
|
Imm-13 |
Parham 3rd. ed. 4ch. 11, pp. 343-376
NEJ M article: 15. Autoimmune Disease 345(5): 340-350 |
Imm-14 |
Parham, ch 12, pp. 437-452 |
Imm-15 |
Parham, ch 12, pp. 364-392 |
Cases |
A and B Groups (see schedule for specific group assignment; lit. list below) |
Imm-16 |
Parham, ch 15 |
Imm-17 |
Parham, ch 16, pp. 489-504
|
NEW ENGLAND JOURNAL OF MEDICINE ARTICLES |
1 |
The Immune System I 343:37-49 |
2 |
The Immune System II 343:108-117 |
3 |
Innate Immunity 343:338-344 |
4 |
The HLA System I |
5 |
The HLA System II |
6 |
T-Cell Function and Migration |
7 |
Primary Immunodeficiency Diseases Due to Defects in Lymphocytes 343:1313-1324 |
8 |
Immunodeficiency Diseases Caused by Defects in Phagocytes 343:1703-1714 |
9 |
Allergy and Allergic Diseases I |
10 |
Allergy and Allergic Diseases II |
11 |
Asthma |
12 |
Tolerance and Autoimmunity |
13 |
Complement I |
14 |
Complement II |
15 |
Autoimmune Disease |
| 16 |
Rheumatoid Arthritis |
| REQUIRED READING FOR SMALL GROUPS |
| Lab 1 |
Methods Lab #1: ELIZA, RIA, WESTERN, IFA |
| Lab 2 |
Methods Lab #2: Flow Cytometry |
| Polio |
1. Nathanson, N. and Fine, P. Poliomyelitis Eradication- a Dangerous Endgame Science 296: 269-270, 2002.
2. Kew et al. Outbreak of Poliomyelitis in Hispaniola Associated with Circulating Type 1 Vaccine-Derived Poliovirus Science 296: 356-359, 2002.
3. Samuel L. Katz, Polio – New challenges in 2006, J Clinical Vir 26 (2006) 163-165
4. Neal Nathanson, Paul Fine: Poliomyelitis Eradication – a Dangerous Endgame. Science Vol 296 12 April 2002
5. Olen Kew, et al.: Outbreak of Poliomyelitis in Hispaniola…, Science, Vol 296 12 April 2002
Review/Read IMM-9 |
| TB |
TB-1 - updated reading (2008)
TB-2 - updated reading (2008)
TB-3 - updated reading (2008) |
| IBD |
1. Hume, G., and Radford-Smith, G.L. 2002. The pathogenesis of Crohn's disease in the 21st century. Pathology34:562-567.
2. Bouma G. Strober W. The immunological and genetic basis of inflammatory bowel disease. 2003 (July) Nature Reviews Immunology. 3(7):521-33.
3. Joshua R. Korzenik, Daniel K. Podolsky Evolving Knowledge and therapy of inflammatory bowel disease, Nature reviews, Vol 5, March 2006
Review/Read IMM-1, IMM-11, IMM-16 |
| BMT |
1. Körbling, M., and Anderlini, P. 2001. Peripheral blood progenitor cells for HPC transplants involving unrelated donors. Blood 98: 2900-2908.
2. Edward A. Copelan, M.D. Hematopoietic Stem-Cell Transplantation N Engl J Med 2006; 354:1813-26
Review/Read IMM-6, Imm14, Fig. 1-1 |
| Asthma |
1. Ahrshad, S.H., and Holgate, S. 2001. The role of IgE in allergen-induced inflammationand the potential for intervention with a humanized monoclonal anti-IgE antibody. Clinical and Experimental Allergy 31:1344-1351.
2. Michael J. Walter, Michael J. Holtzman, A centennial History of Research on Asthma Pathogenesis. Pulmonary and Critical Care Medicine, Am J Respir Cell Mol Biol Vol. 32. pp 483-489, 2005
Review/Read IMM-8 and IMM-13 |
| SLE |
1. Mok, C.C., and Lau, C.S. 2003. Pathogenesis of systemic lupus erythematosus. Journal of Clinical Pathology 56:481-490.
2. Jennifer A. Anolik, Martin Aringer: New treatments for SLE: cell-depleting and anti-cytokine therapies; Best Practice and Research Clinical Rheumatology, Vol 19 no. 5 pp 859-878 2005
Review/Read 9, IMM-10, IMM-16 |