Pathology Thread

OBJECTIVES

1. Gross Anatomy and Histology

After completing this section you will be able to:

• List the various parts and structures that form the ovary
• describe the gross anatomy and histology of the ovary
• describe the physiologic changes that occur in the ovary with each menstrual cycle

2. Nonneoplastic Lesions

After completing this section you will be able to:

• list the common nonneoplastic lesions of the ovary
• understand and describe clinical features and relevant associations
• predict clinical outcome, suggest treatment and predict response to treatment

3. Neoplasms

After completing this section you will know:

• the main groups of ovarian neoplasms
• which group is most common
• which group accounts for the most deaths
• which group presents with hormonal activity and which produces tumor markers
• which group has analogous testicular tumors

1. Epithelial Tumors

After completing this section you will:

• know the common subtypes and which are most often bilateral
• match the various subtypes with epithelium in other parts of the female genital tract
• understand the concept of borderline tumors and how to distinguish them from carcinomas
• be able to describe clinical features including relevant associations
• be able to suggest possible clinical outcomes and response to treatment

2. Germ Cell Tumors

After completing this section you will:

• understand how germ cell tumors originate
• know the commonest type
• be able to describe clinical features including relevant associations
• know which tumor produces which marker
• predict possible clinical outcomes and response to treatment

3. Sex Cord-Stromal Tumors

After completing this section you will:

• understand the origins of these tumors
• know which are feminizing, virilizing or both
• describe clinical features and relevant associations
• predict possible clinical outcomes/behavior and response to treatment
  

4. Miscellaneous Ovarian Tumors

After completing this section you will know:

• The various mixed epithelial-mesenchymal tumors, their components and clinical behavior
• the commonest primary site of metastasis to the ovary
• what Krukenberg tumor is and the common primary sites from which it may arise