Pathology > Study Images > Male Genitals > Penis > Infectious Diseases
Objectives Anat & Hist Congenital Infectious Benign Malignant

III. Infectious Diseases


After completing this section you will be able to:

  • describe the various types of inflammatory conditions that involve the penis
  • indicate etiologic agents
  • describe and identify clinical lesions

A plethora of viral, bacterial, fungal, and protozoan organisms may infect the penis via both venereal and non-venereal transmission.

  1. Balanoposthitis

This is nonspecific penile infection with inflammation of both the glans (balanitis) and the prepuce. Usually the patient has a phimosis or a large, redundant prepuce that interferes with cleanliness. The offending organism is frequently a Staphylococcal or Streptococcal species but may also be caused by Candida albicans. The condition may lead to frank ulceration of the glans.

  1. Condyloma accuminatum

This is a viral infection caused by the human papillomavirus (HPV) type 6 or 11 that produces a warty growth. It is spread by venereal or by less direct means.

The lesions occur, most often, about the coronal sulcus and inner surface of the prepuce as single or multiple, sessile or pedunculated, red papillary excrescences of varying sizes.

Note the warty masses on the glans of the penis.

Multiple large warty growths are present on the ventral aspect of the glans and neck of the penis.

Histologically, the lesions present as branching, finger-like, papillary connective tissue stroma covered by thickened, hyperplastic epithelium, which may show excessive surface keratinization. Koilocytes may be noted in the superficial zone of the epithelium. Cellular atypia is absent.

  1. Condyloma lata (Syphilitic wart)

This occurs in secondary syphilis and develops 2 to 8 weeks after the primary chancre. It is highly infectious and presents as gray-white to erythematous, painless, broad, moist plaques.

Condyloma lata. White plaques are present on the skin of the shaft and prepuce.

Objectives Anat & Hist Congenital Infectious Benign Malignant