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> Study Images > Male
Genitals > Penis > Benign Conditions
IV. Benign Conditions
After completing this section you will
be able to:
- describe the clinical features of Peyronies disease
- state relevant associations and complication
- Peyronie's Disease (Penile Fibromatosis)
This is a disease of unknown cause characterized by focal, fibrous induration
of the shaft of the penis associated with abnormal curvature and painful erection.
It is associated with Dupuytren's contracture (palmar fibromatosis), which
is present in about 25% of cases.
Histologically, dense fibro-collagenous tissue is present in the tunica albuginea
or between the tunica and the penile fascia.
The lesion usually recurs after surgical removal.
This refers to unwanted, inappropriate (unrelated to sexual activity), persistent,
painful erection. Priapism is distinguished from normal erection by absence
of tumescence of the glans. It may be idiopathic, associated with sickle cell
disease, chronic granulocytic leukemia, spinal cord injury, or secondary to
injection of vasodilator agents (e.g. PGE1) into the penis, drugs (e.g. trazadone),
thrombosis of the penile veins or to adrenergic-mediated mechanism for detumescence.
In priapism of sickle cell disease, the corpora cavernosa are usually engorged
and the glans and corpus spongiosum are spared. In a minority however, tricorporal
priapism occurs. Priapism, especially tricorporal, may eventuate in impotence.