III. Infectious Diseases
After completing this section you
will be able to:
- describe the various types of inflammatory conditions
that involve the penis
- indicate etiologic agents
- describe and identify clinical lesions
A plethora of viral, bacterial, fungal, and protozoan organisms may infect
the penis via both venereal and non-venereal transmission.
This is nonspecific penile infection with inflammation of both the glans
(balanitis) and the prepuce. Usually the patient has a phimosis or a large,
redundant prepuce that interferes with cleanliness. The offending organism
is frequently a Staphylococcal or Streptococcal species but may also be caused
by Candida albicans. The condition may lead to frank ulceration of the glans.
- Condyloma accuminatum
The lesions occur, most often, about the coronal sulcus and inner surface
of the prepuce as single or multiple, sessile or pedunculated, red papillary
excrescences of varying sizes.
This is a viral infection caused by the human papillomavirus (HPV) type 6
or 11 that produces a warty growth. It is spread by venereal or by less direct
Note the warty masses on the glans of the penis.
Multiple large warty growths are present on the ventral aspect of the glans
and neck of the penis.
Histologically, the lesions present as branching, finger-like, papillary
connective tissue stroma covered by thickened, hyperplastic epithelium, which
may show excessive surface keratinization. Koilocytes may be noted in the
superficial zone of the epithelium. Cellular atypia is absent.
- Condyloma lata (Syphilitic wart)
This occurs in secondary syphilis and develops 2 to 8 weeks after the primary
chancre. It is highly infectious and presents as gray-white to erythematous,
painless, broad, moist plaques.
Condyloma lata. White plaques are present on the skin of the shaft and prepuce.