The peripheral blood platelet count ranges from 150 - 450
x 10 /L.
About 2/3 of platelets circulate, while 1/3 are in the
splenic pool or other extravascular locations.
During its lifespan the average megakaryocyte (MK) gives
rise to approximately 4,000 platelets which live an average
of 9-12 days.
In the steady state, where platelet production = platelet
destruction, daily production is 30,000 - 40,000 /uL.
As with RBCs platelet production can be increased up to
8x normal if needed.