Thyroid Ultrasound > Top 10 Pathology > 10. de Quervain's Thyroiditis

De Quervain's Thyroiditis

Subacute granulomatous (de Queurvain's) thyroiditis is a self-limited painful thyroid condition associated with a clinical course of hyperthyroidism, hypothyroidism, and return to normal thyroid function. On I123 scintigraphy, generally very little uptake is noted, because the release of preformed thyroid hormone from the thyroid gland suppresses TSH levels, which are needed to express the sodium-iodine (Na-I) symporter responsible for iodine uptake into the gland. Of note is that a postpartum type of subacute thyroiditis exists.

On sonography, a diffusely enlarged somewhat poorly marginated gland is present and color Doppler is usually normal or decreased (distinguishable from the extensive severe hypervascular appearance of Graves' disease).

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