Pediatric Radiology > Musculoskeletal > Metabolic Diseases > Hemophilia
Hemophilia is a bleeding disorder which can have profound musculoskeletal sequelae. Roughly 90% of patients with hemophilia suffer from spontaneous hemarthroses, many of which are recurrent. Typically, these hemarthroses are monoarticular and occur most frequently in the knee > elbow > ankle. Hemosiderin is deposited within the synovium of the affected joint leading to synovial hypertrophy, which in turn can lead to destruction of the underlying articular cartilage.
|Hemophilic arthropathy in a 7-year old male. AP and lateral radiographs of the right knee demonstrate joint irregularity and an effusion. There is widening of the intracondylar notch. Also note the squaring and epiphyseal overgrowth involving the tibia and femur.|
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