Pediatric Radiology > Neurological > Neurocutaneous Syndromes > Tuberous Sclerosis
The classic triad of seizures, mental retardation, and adenoma sebaceum is associated with tuberous sclerosis (TS), another autosomal dominant disorder. The most common imaging finding are tubers, which are hamartomas along the subependymal surface and cortex. These lesions tend to calcify. White matter glial abnormalities may also be present.
|Precontrast CT, Giant Cell Astrocytoma||Postcontrast CT, Giant Cell Astrocytoma|
|A tuber near the foramen of Monro may rapidly enlarge and lead to obstructive hydrocephalus, referred to as a subependymal giant cell astrocytoma.|
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